Separation anxiety and noise aversion are common behavioral problems in dogs. A novel botanical anxiolytic product containing Souroubea app. vine and Platanus spp. bar was evaluated for safety in dogs at a recommended dose of 1 mg/kg body weight (BW).

In the study, 16 dogs were given either a placebo or the formulation at five times the intended dose for 28 days.  The dogs were monitored for adverse effects. 

The results of the study concluded that there were no clinically significant adverse effects noted though clinical observation, physical examination, bloodwork, and urinalysis evaluation. 

Read the full study here: 

Safety evaluation of a new anxiolytic product containing botanicals Souroubea spp. and Platanus spp. in dogs